Evolving phenotype of systemic lupus erythematosus patients and it's correlation with antibody against c1q

نویسندگان

چکیده

Backgrounds: Autoantibodies against C1q are strongly linked to immune-complex disorders like systemic lupus erythematosus (SLE). Although anti-C1q antibodies have received much interest in the recent years, their biological functions remain unclear. Aim and objectives: The main aim of this study was analyze phenotype at first presentation during follow-up Qena university hospital. Subjects methods: This cross-sectional conducted on 100 patients. Results: Regarding relation between activity antibody we found that there were highly statistically significant differences groups according antibody. We also with increasing patients when comparing without activity. Conclusion: Anti-C1q associated disease SLE patients, suggesting it may be a reliable, sensitive non-invasive serological marker for identification active disease.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Anti-C1Q Antibody as A Marker In Systemic Lupus Erythematosus

Objective: To study the correlation of anti C1q antibodies with disease activity in patients with systemic lupus erythematosus (SLE). Study Design: Cross sectional, observational study. Place and Duration of study: The Department of Immunology, Armed Forces Institute of Pathology, Rawalpindi in collaboration with Military Hospital, Rawalpindi, Pakistan Institute of Medical Sciences, Islamabad a...

متن کامل

Correlation of Serum Soluble Interleukin-7 Receptor and Anti-C1q Antibody in Patients with Systemic Lupus Erythematosus

Background. Serum concentrations of soluble interleukin-7 receptor (sIL-7R) and anti-C1q antibody have recently been identified as unique serological markers for lupus nephritis (LN) in patients with systemic lupus erythematosus (SLE). In this study, we evaluated the correlation of serum sIL-7R and anti-C1q in SLE patients. Methods. Sera from 134 patients with SLE and 84 healthy cohorts were te...

متن کامل

C1q Deficiency and Neuropsychiatric Systemic Lupus Erythematosus

C1q deficiency is a rare immunodeficiency, which is strongly associated with the development of systemic lupus erythematosus (SLE). A mutation in one of the C1q genes can either lead to complete deficiency or to low C1q levels with C1q polypeptide in the form of low-molecular weight (LMW) C1q. Patients with C1q deficiency mainly present with cutaneous and renal involvement. Although less freque...

متن کامل

Survival rate of patients with systemic Lupus Erythematosus

Background: Due to infections, cardio-vascular involvement and renal insufficiency, patients with systemic lupus erythematosus live shorter than usual. Objective: To determine the mean survival rate of SLE patients. Patients and Methods: 62 SLE patients admitted in the hospitals of Kerman University of Medical Sciences from 1369 to 1380 were included in this study. The demographic variabl...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: International Journal of Health Sciences (IJHS)

سال: 2022

ISSN: ['2550-6978', '2550-696X']

DOI: https://doi.org/10.53730/ijhs.v6ns6.11181